ACTIVATOR PROTEIN 1
\ˈaktɪvˌe͡ɪtə pɹˈə͡ʊtiːn wˈɒn], \ˈaktɪvˌeɪtə pɹˈəʊtiːn wˈɒn], \ˈa_k_t_ɪ_v_ˌeɪ_t_ə p_ɹ_ˈəʊ_t_iː_n w_ˈɒ_n]\
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A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.