ADELARDO LOPEZ DE AYALA
\ɐdɪlˈɑːdə͡ʊ lˈə͡ʊpɛz dəɹ a͡ɪˈɑːlə], \ɐdɪlˈɑːdəʊ lˈəʊpɛz dəɹ aɪˈɑːlə], \ɐ_d_ɪ_l_ˈɑː_d_əʊ l_ˈəʊ_p_ɛ_z d_ə_ɹ aɪ__ˈɑː_l_ə]\
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A Spanish dramatist; born at Guadalcanal, Badajoz, March 1829; died Dec. 30, 1879. After studying law in Seville, he went to Madrid, where he devoted himself entirely to poetry and speedily won national fame. His first drama, "A Statesman" (1851), met with immediate success, and was followed in the same year by "The Two Noblemen" and "Penalty and Pardon". To the modern comedy of manners, his specific domain, he first contributed "The Glass Roof", and in 1861 attained to wide reputation with "Percentage". Of his other works the most noteworthy are: "The Modern Don Juan" (1863); and "Consuclo" (1878), a drama. He has also written beautiful sonnets.
By Charles Dudley Warner
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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