ALLAN G PINKERTON

\ˈalən d͡ʒˈiː pˈɪŋkətən], \ˈalən d‍ʒˈiː pˈɪŋkətən], \ˈa_l_ə_n dʒ_ˈiː p_ˈɪ_ŋ_k_ə_t_ə_n]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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