ANTASTHENIC
\ˌantɐsθˈɛnɪk], \ˌantɐsθˈɛnɪk], \ˌa_n_t_ɐ_s_θ_ˈɛ_n_ɪ_k]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.