ANTISPASIS
\ˌantɪspˈasiz], \ˌantɪspˈasiz], \ˌa_n_t_ɪ_s_p_ˈa_s_i_z]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.