ANTISPASMODICK

\ˌantɪspˈazmədˌɪk], \ˌantɪspˈazmədˌɪk], \ˌa_n_t_ɪ_s_p_ˈa_z_m_ə_d_ˌɪ_k]\
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1790 - A Complete Dictionary of the English Language
By Thomas Sheridan

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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