BID AND ASKED
\bˈɪd and ˈaskt], \bˈɪd and ˈaskt], \b_ˈɪ_d a_n_d ˈa_s_k_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.