BLACKWATER FEVER

\blˈakwɔːtə fˈiːvə], \blˈakwɔːtə fˈiːvə], \b_l_ˈa_k_w_ɔː_t_ə f_ˈiː_v_ə]\
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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland
 
1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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