CALDWELL-LUC OPERATION

\kˈɒldwɛllˈuːk ˌɒpəɹˈe͡ɪʃən], \kˈɒldwɛllˈuːk ˌɒpəɹˈe‍ɪʃən], \k_ˈɒ_l_d_w_ɛ_l_l_ˈuː_k ˌɒ_p_ə_ɹ_ˈeɪ_ʃ_ə_n]\

Definitions of CALDWELL-LUC OPERATION

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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