CAROLIS SYNDROME
\kˈaɹəlˌiz sˈɪndɹə͡ʊm], \kˈaɹəlˌiz sˈɪndɹəʊm], \k_ˈa_ɹ_ə_l_ˌi_z s_ˈɪ_n_d_ɹ_əʊ_m]\
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Congenital cystic dilatation of the intrahepatic bile ducts. It consists of 2 types: simple, with bile duct dilatation or ectasia alone, and complex, with associated extensive hepatic fibrosis and portal hypertension. Benign renal tubular ectasia is associated with both types.
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.