CATACHRISIS
\kˈatɐt͡ʃɹˌɪsiz], \kˈatɐtʃɹˌɪsiz], \k_ˈa_t_ɐ_tʃ_ɹ_ˌɪ_s_i_z]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.