CHILBLAINED
\t͡ʃˈɪlble͡ɪnd], \tʃˈɪlbleɪnd], \tʃ_ˈɪ_l_b_l_eɪ_n_d]\
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having chilblains; "her poor chilblained hands"
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.