CIRCUMROTATE
\sˈɜːkəmɹˌə͡ʊte͡ɪt], \sˈɜːkəmɹˌəʊteɪt], \s_ˈɜː_k_ə_m_ɹ_ˌəʊ_t_eɪ_t]\
Definitions of CIRCUMROTATE
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.