CLASSIC MIGRAINE
\klˈasɪk mˈa͡ɪɡɹe͡ɪn], \klˈasɪk mˈaɪɡɹeɪn], \k_l_ˈa_s_ɪ_k m_ˈaɪ_ɡ_ɹ_eɪ_n]\
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A condition characterized by throbbing headaches which are preceded or accompanied by reversible symptoms that reflect cortical or brain stem dysfunction. The most common type of aura consists of a positive visual phenomenon, usually in the form of a scintillating scotoma. An aura may also take the form of other focal neurologic symptoms or signs, including loss of sensation or weakness in an extremity. In general, the aura precedes the headache by less than 60 minutes, develops over 4 minutes or longer, and has a duration of less than one hour. (From Adams et al., Principles of Neurology, 6th ed, p172; Cephalalgia 1988;8:Suppl 7:1-96)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.