CLEMENT MAROT

\klˈɛmənt mˈaɹɒt], \klˈɛmənt mˈaɹɒt], \k_l_ˈɛ_m_ə_n_t m_ˈa_ɹ_ɒ_t]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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