DECOCTUM ZITTMANNI

\dɪkˈɒktəm zˈɪtmɐnˌi], \dɪkˈɒktəm zˈɪtmɐnˌi], \d_ɪ_k_ˈɒ_k_t_ə_m z_ˈɪ_t_m_ɐ_n_ˌi]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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