DEXTROMETHORPHAN, (+ ) ISOMER
\dˈɛkstɹə͡ʊmθˌɔːfən], \dˈɛkstɹəʊmθˌɔːfən], \d_ˈɛ_k_s_t_ɹ_əʊ_m_θ_ˌɔː_f_ə_n]\
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The d-isomer of the codeine analog of LEVORPHANOL. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is a NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is used widely as an antitussive agent, and is also used to study the involvement of glutamate receptors in neurotoxicity.
By DataStellar Co., Ltd
