DI GUGLIELMO DISEASE
\dˈa͡ɪ ɡʌɡlˈiːlmə͡ʊ dɪzˈiːz], \dˈaɪ ɡʌɡlˈiːlməʊ dɪzˈiːz], \d_ˈaɪ ɡ_ʌ_ɡ_l_ˈiː_l_m_əʊ d_ɪ_z_ˈiː_z]\
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A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.