DIEDRICH TIEDEMANN

\dˈiːdɹɪt͡ʃ tˈa͡ɪdɪmˌan], \dˈiːdɹɪt‍ʃ tˈa‍ɪdɪmˌan], \d_ˈiː_d_ɹ_ɪ_tʃ t_ˈaɪ_d_ɪ_m_ˌa_n]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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