ELTROXINE
\ˈɛltɹəksˌa͡ɪn], \ˈɛltɹəksˌaɪn], \ˈɛ_l_t_ɹ_ə_k_s_ˌaɪ_n]\
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The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
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