EXTRAMEMBRANOUS GLOMERULOPATHY
\ˈɛkstɹəmˌɛmbɹanəs ɡlˌɒməɹuːlˈɒpəθɪ], \ˈɛkstɹəmˌɛmbɹanəs ɡlˌɒməɹuːlˈɒpəθɪ], \ˈɛ_k_s_t_ɹ_ə_m_ˌɛ_m_b_ɹ_a_n_ə_s ɡ_l_ˌɒ_m_ə_ɹ_uː_l_ˈɒ_p_ə_θ_ɪ]\
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A disease of the glomerulus manifested clinically by proteinuria, and sometimes by other features of the nephrotic syndrome. It is histologically characterized by deposits in the glomerular capillary wall between the epithelial cell and the basement membrane and a thickening of the membrane. Also characteristic are outward projections of the membrane between the epithelial deposits in the form of "spikes". There is some agreement that the deposits are antigen-antibody complexes.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.