EXTRAPYRAMIDAL RIGIDITY
\ˈɛkstɹəpˌɪɹɐmˌɪdə͡l ɹɪd͡ʒˈɪdɪti], \ˈɛkstɹəpˌɪɹɐmˌɪdəl ɹɪdʒˈɪdɪti], \ˈɛ_k_s_t_ɹ_ə_p_ˌɪ_ɹ_ɐ_m_ˌɪ_d_əl ɹ_ɪ_dʒ_ˈɪ_d_ɪ_t_i]\
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Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.