FREEZE SUBSTITUTION

\fɹˈiːz sˌʌbstɪtjˈuːʃən], \fɹˈiːz sˌʌbstɪtjˈuːʃən], \f_ɹ_ˈiː_z s_ˌʌ_b_s_t_ɪ_t_j_ˈuː_ʃ_ə_n]\

Definitions of FREEZE SUBSTITUTION

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2010 - Medical Dictionary Database
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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