GANGLIONIC BLOCKING AGENTS
\ɡˌaŋɡlɪˈɒnɪk blˈɒkɪŋ ˈe͡ɪd͡ʒənts], \ɡˌaŋɡlɪˈɒnɪk blˈɒkɪŋ ˈeɪdʒənts], \ɡ_ˌa_ŋ_ɡ_l_ɪ__ˈɒ_n_ɪ_k b_l_ˈɒ_k_ɪ_ŋ ˈeɪ_dʒ_ə_n_t_s]\
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Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.