GLOCHIDIUM
\ɡlət͡ʃˈɪdi͡əm], \ɡlətʃˈɪdiəm], \ɡ_l_ə_tʃ_ˈɪ_d_iə_m]\
Definitions of GLOCHIDIUM
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.