GRAFFIS CHLOROLEUKEMIC STRAIN

\ɡɹˈafiz klˌɔːɹə͡ʊluːkˈɛmɪk stɹˈe͡ɪn], \ɡɹˈafiz klˌɔːɹə‍ʊluːkˈɛmɪk stɹˈe‍ɪn], \ɡ_ɹ_ˈa_f_i_z k_l_ˌɔː_ɹ_əʊ_l_uː_k_ˈɛ_m_ɪ_k s_t_ɹ_ˈeɪ_n]\

Definitions of GRAFFIS CHLOROLEUKEMIC STRAIN

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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