GYRA PROTEIN
\d͡ʒəɹ ɐ pɹˈə͡ʊtiːn], \dʒəɹ ɐ pɹˈəʊtiːn], \dʒ_ə_ɹ ɐ p_ɹ_ˈəʊ_t_iː_n]\
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A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting two A and two B subunits. In the presence of ATP, gyrase is able to convert relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase.
By DataStellar Co., Ltd
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Platidiam
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