HALEK VITEZLAV

\hˈe͡ɪlək vˈa͡ɪtzlav], \hˈe‍ɪlək vˈa‍ɪtzlav], \h_ˈeɪ_l_ə_k v_ˈaɪ_t_z_l_a_v]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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