HASH OVER
\hˈaʃ ˈə͡ʊvə], \hˈaʃ ˈəʊvə], \h_ˈa_ʃ ˈəʊ_v_ə]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.