HIGH-DENSITY LIPOPROTEIN
\hˈa͡ɪdˈɛnsɪti lˈɪpəpɹˌə͡ʊtiːn], \hˈaɪdˈɛnsɪti lˈɪpəpɹˌəʊtiːn], \h_ˈaɪ_d_ˈɛ_n_s_ɪ_t_i l_ˈɪ_p_ə_p_ɹ_ˌəʊ_t_iː_n]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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