HISTONE KINASE P34(CDC2)
\hˈɪstə͡ʊn kˈɪne͡ɪs pˈiː θˈɜːtifˈɔː sˌiːdˌiːsˈiː tˈuː], \hˈɪstəʊn kˈɪneɪs pˈiː θˈɜːtifˈɔː sˌiːdˌiːsˈiː tˈuː], \h_ˈɪ_s_t_əʊ_n k_ˈɪ_n_eɪ_s p_ˈiː θ_ˈɜː_t_i_f_ˈɔː__ s_ˌiː_d_ˌiː_s_ˈiː t_ˈuː]\
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Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the cell cycle. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of p34cdc2 is achieved when it is fully dephosphorylated. Protein p34cdc2, the product of the cdc2 gene in Schizosaccharomyces pombe, should not be confused with the unrelated product of the CDC2 gene in Saccharomyces cerevisiae that forms the large subunit of DNA polymerase III.
By DataStellar Co., Ltd
