IMPORTIN BETA
\ɪmpˈɔːtɪn bˈiːtə], \ɪmpˈɔːtɪn bˈiːtə], \ɪ_m_p_ˈɔː_t_ɪ_n b_ˈiː_t_ə]\
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Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.
By DataStellar Co., Ltd
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