JACOB ABBOTT

\d͡ʒˈe͡ɪkəb ˈabət], \d‍ʒˈe‍ɪkəb ˈabət], \dʒ_ˈeɪ_k_ə_b ˈa_b_ə_t]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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