JOHN ZAMBELIOS

\d͡ʒˈɒn zambˈɛlɪˌə͡ʊz], \d‍ʒˈɒn zambˈɛlɪˌə‍ʊz], \dʒ_ˈɒ_n z_a_m_b_ˈɛ_l_ɪ__ˌəʊ_z]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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