KOESTER'S NODULE
\kˈə͡ʊstəz nˈɒdjuːl], \kˈəʊstəz nˈɒdjuːl], \k_ˈəʊ_s_t_ə_z n_ˈɒ_d_j_uː_l]\
Definitions of KOESTER'S NODULE
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.