LAPPING-ENGINE

\lˈapɪŋˈɛnd͡ʒɪn], \lˈapɪŋˈɛnd‍ʒɪn], \l_ˈa_p_ɪ_ŋ_ˈɛ_n_dʒ_ɪ_n]\

Definitions of LAPPING-ENGINE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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