LARDENNOIS' METHOD

\lˈɑːdənwˌɑː mˈɛθəd], \lˈɑːdənwˌɑː mˈɛθəd], \l_ˈɑː_d_ə_n_w_ˌɑː m_ˈɛ_θ_ə_d]\

Definitions of LARDENNOIS' METHOD

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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