LICHEN SYPHILITICUS

\lˈa͡ɪkən sˌa͡ɪfɪlˈɪtɪkəs], \lˈa‍ɪkən sˌa‍ɪfɪlˈɪtɪkəs], \l_ˈaɪ_k_ə_n s_ˌaɪ_f_ɪ_l_ˈɪ_t_ɪ_k_ə_s]\

Definitions of LICHEN SYPHILITICUS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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