MEDIGOXIN
\mˈɛdɪɡˌɒksɪn], \mˈɛdɪɡˌɒksɪn], \m_ˈɛ_d_ɪ_ɡ_ˌɒ_k_s_ɪ_n]\
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A semisynthetic digitalis glycoside with the general properties of DIGOXIN but more rapid onset of action. Its cardiotonic action is prolonged by its demethylation to DIGOXIN in the liver. It has been used in the treatment of congestive heart failure (HEART FAILURE, CONGESTIVE).
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.