MELANCHOLIA OF PUBERTY

\mˌɛlənkˈə͡ʊli͡əɹ ɒv pjˈuːbəti], \mˌɛlənkˈə‍ʊli‍əɹ ɒv pjˈuːbəti], \m_ˌɛ_l_ə_n_k_ˈəʊ_l_iə_ɹ ɒ_v p_j_ˈuː_b_ə_t_i]\

Definitions of MELANCHOLIA OF PUBERTY

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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