MELILOTUS OFFICINALIS

\mˈɛlɪlˌɒtəs əfˌɪsɪnˈɑːliz], \mˈɛlɪlˌɒtəs əfˌɪsɪnˈɑːliz], \m_ˈɛ_l_ɪ_l_ˌɒ_t_ə_s ə_f_ˌɪ_s_ɪ_n_ˈɑː_l_i_z]\
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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