NECROTIZING ULCERATIVE GINGIVITIDES
\nˈɛkɹətˌa͡ɪzɪŋ ˈʌlsəɹətˌɪv d͡ʒˈɪŋɡɪvˌɪta͡ɪdz], \nˈɛkɹətˌaɪzɪŋ ˈʌlsəɹətˌɪv dʒˈɪŋɡɪvˌɪtaɪdz], \n_ˈɛ_k_ɹ_ə_t_ˌaɪ_z_ɪ_ŋ ˈʌ_l_s_ə_ɹ_ə_t_ˌɪ_v dʒ_ˈɪ_ŋ_ɡ_ɪ_v_ˌɪ_t_aɪ_d_z]\
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An acute or chronic gingival infection characterized by redness and swelling, necrosis extending from the interdental papillae along the gingival margins, pain, hemorrhage, necrotic odor, and often a pseudomembrane. The condition may extend to the oral mucosa, tongue, palate, or pharynx.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.