PHOTOCHROMOSCOPE

\fˌə͡ʊtə͡ʊkɹˈə͡ʊməskˌə͡ʊp], \fˌə‍ʊtə‍ʊkɹˈə‍ʊməskˌə‍ʊp], \f_ˌəʊ_t_əʊ_k_ɹ_ˈəʊ_m_ə_s_k_ˌəʊ_p]\
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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