R51619

\ˈɑː fˈɪftiwˈɒn θˈa͡ʊzənd sˈɪkshˈʌndɹədən nˈa͡ɪntiːn], \ˈɑː fˈɪftiwˈɒn θˈa‍ʊzənd sˈɪkshˈʌndɹədən nˈa‍ɪntiːn], \ˈɑː f_ˈɪ_f_t_i_w_ˈɒ_n θ_ˈaʊ_z_ə_n_d_ s_ˈɪ_k_s_h_ˈʌ_n_d_ɹ_ə_d_ə_n n_ˈaɪ_n_t_iː_n]\

Definitions of R51619

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2010 - Medical Dictionary Database
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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