ROCHER'S SIGN
\ɹˈɒt͡ʃəz sˈa͡ɪn], \ɹˈɒtʃəz sˈaɪn], \ɹ_ˈɒ_tʃ_ə_z s_ˈaɪ_n]\
Definitions of ROCHER'S SIGN
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.