SCANNING DYSARTHRIAS
\skˈanɪŋ da͡ɪsˈɑːθɹi͡əz], \skˈanɪŋ daɪsˈɑːθɹiəz], \s_k_ˈa_n_ɪ_ŋ d_aɪ_s_ˈɑː_θ_ɹ_iə_z]\
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Disorders of speech articulation caused by imperfect coordination of pharnyx, larnyx, tongue, or face muscles. This may result from CRANIAL NERVE DISEASES; NEUROMUSCULAR DISEASES; CEREBELLAR DISEASES; BASAL GANGLIA DISEASES; BRAIN STEM diseases; or diseases of the corticobulbar tracts (see PYRAMIDAL TRACTS). The cortical language centers are intact in this condition. (From Adams et al., Principles of Neurology, 6th ed, p489)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.