SIBILANT RALE

\sˈɪbɪlənt ɹˈe͡ɪl], \sˈɪbɪlənt ɹˈe‍ɪl], \s_ˈɪ_b_ɪ_l_ə_n_t ɹ_ˈeɪ_l]\

Definitions of SIBILANT RALE

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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