TH1 CELLS
\tˌiːˈe͡ɪt͡ʃ wˈɒn sˈɛlz], \tˌiːˈeɪtʃ wˈɒn sˈɛlz], \t_ˌiː__ˈeɪ_tʃ w_ˈɒ_n s_ˈɛ_l_z]\
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Subset of helper-inducer T-lymphocytes which synthesize and secrete interleukin-2, gamma-interferon, and interleukin-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.