TOPOISOMERASE I
\tˈɒpɔ͡ɪsˌə͡ʊmɹe͡ɪz ˈa͡ɪ], \tˈɒpɔɪsˌəʊmɹeɪz ˈaɪ], \t_ˈɒ_p_ɔɪ_s_ˌəʊ_m_ɹ_eɪ_z ˈaɪ]\
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DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.