TRANSLATION STOP SIGNALS
\tɹanslˈe͡ɪʃən stˈɒp sˈɪɡnə͡lz], \tɹanslˈeɪʃən stˈɒp sˈɪɡnəlz], \t_ɹ_a_n_s_l_ˈeɪ_ʃ_ə_n s_t_ˈɒ_p s_ˈɪ_ɡ_n_əl_z]\
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Any codon that signals the termination of genetic translation (TRANSLATION, GENETIC). PEPTIDE TERMINATION FACTORS bind to the stop codon and trigger the hydrolysis of the aminoacyl bond connecting the completed polypeptide to the tRNA. Terminator codons do not specify amino acids.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.